Education:

Undergraduate: 1962-1966 Dartmouth College 1966 B.A.

Medical School: 1966-1970 University of Chicago 1970 M.D.
School of Medicine
Chicago, Illinois

Internship: 1970-1971 University of Chicago
School of Medicine
Chicago, Illinois

Post Graduate Training:

U.S.P.H.S. Trainee Residency in Ophthalmology
University of Chicago
1971-1973

U.S.P.H.S. Trainee and Chief Resident in Ophthalmology
University of Chicago
1973-1974

University of Chicago Retina Fellowship
School of Medicine
Department of Ophthalmology
1974-1975

Licenses and Certifications:

Illinois Medical License, 1970
California Medical License, No. G28739, January 1975
Certified, American Board of Ophthalmology, October 1976

Membership in Scientific Societies:

Association for Research in Vision and Ophthalmology, June 1972
Frederick C. Cordes Eye Society, 1976
Pacific Coast Ophthalmological Society, May 1978
American Academy of Ophthalmology, October 1978
Peninsula Eye Society, January 1980
The Retina Society, September 1983
The Vitreous Society, December 1983
The Macula Society, January 1990

Editorial Boards:

Investigative Ophthalmology, 1989

Principle Positions Held:

Assistant Professor
University of Chicago
Chicago, Illinois of Ophthalmology
1974-1975

Assistant Clinical Professor
University of California
San Francisco, California of Ophthalmology
1975-1979

Associate Clinical Professor
University of California
San Francisco, California of Ophthalmology
1979-1982

Associate Professor
University of California
San Francisco, California of Ophthalmology
1982-1986

Professor of Ophthalmology
University of California
San Francisco, California
1986-1989

Clinical Professor
University of California
San Francisco, California of Ophthalmology
1989-Present

Francis I. Proctor Foundation Research Associate
for Research in Ophthalmology,
University of California,
San Francisco, California
1989-Present

Veterans Admin. Hospital Acting Chief
San Francisco, California of Ophthalmology
1975-1976

Veterans Admin. Hospital Director, Vitreoretinal
San Francisco, California Services
1975-1990

Northern California Sickle Ophthalmic Consultant
Cell Screening Program,
San Francisco General Hospital
San Francisco, California
1982-1986

Ancilliary Positions Held Concurrently:

1975-1989 Fluorescein Angiography Member
Diagnostic Service, UCSF

1985-Present PVR Study Group, UCSF Director

1985-1989 Uveitis Survey, UCSF Co-Director

Honors and Awards:

Phi Beta Kappa, Darmouth College

Alpha Omega Alpha, University of Chicago

William A. Fisher Award - (Best paper presented to Chicago Ophthalmologic Society)

National Film Award, American Film Writers Association
(Best 16-mm film designed to be primarily instruction for medical professionals: “Microsurgical Vitrectomy and Lensectomy Instrumentation in Anterior Chamber Reconstruction”)

American Academy of Ophthalmology Honor Award

Other University Service:

Program Chairman, Vitrectomy Microsurgery Workshops, sponsored by Extended Programs in Medical Education, UCSF, April 21-22 and April 28-29, 1978.

Program Chairman, Vitrectomy Symposium and Workshops, sponsored by Extended Programs in Medical Education, UCSF, April 18-20, 1979.

Departmental Representative, Extended Programs in Medical Education Committee on Use of Video Materials in Continuing Education, UCSF, April 8, 1981.

Program Co-Chairman, Controversies in Retinal Disease, sponsored by Extended Programs in Medical Education, December 1983.

Program Chairman, Uveitis Frontiers, Extended Program in Medical Education, September 16-17, 1989.

Teaching:

Medical Students:
No. of Person
Course, Title, Students, Units, Hrs, Yr From To, in Charge

110 Core Clinical
Clerkship in General
Surgery, VAMC, 30-40, 10, 320, 1975-Present, L. Way

House Staff:
Hours/Week Person
Group Taught Per Year, From To, in Charge

454 Clinical
Ophthalmology (VA) 20, 1975-Present, J. Stanley

454 Clinical
Ophthalmology (UC) 2, 1975-Present, S. Kramer

402 Retina Lecture
Series (UC) 3, 1975-Present, A. Irvine

Professional Postdoctural Students and
Fellows Under My Principal Direction:

Esther Santos, M.D. June 1976 – July 1977
Rajbir Singh, M.D. January 1978 – June 1978
Maeve McDermott, F.R.C.S. January 1981 – December 1981
Daniel Madeira, M.D. August 1986 – September 1981
Li Junping (Heart Fellow) August 1989 – January 1990

Teaching Aids Prepared:

Movie: Current Concepts in Anterior Segment Reconstruction. Anterior and Posterior Vitrectomy.
16 mm, 18 minutes, color and sound, September 1977.

Movie: Microsurgical Vitrectomy and Lensectomy Instrumentation in Anterior Chamber Reconstruction.
16 mm, 22 minutes, color and sound, May 1978.

Laboratory Vitrectomy Teaching Videotapes:

Three 30-minute color videotapes utilizing cow eyes and pig eyes to demonstrate techniques for the use of vitrectomy instrumentation in anterior and posterior segment eye surgery, April 23, 1978.

Laboratory Vitrectomy Teaching Manuals:

Vitrectomy Instrumentation:
Anterior Segment Techniques, April 1979

Manual 1 – Instrumentation
Manual 2 – Open-Sky Vitrectomy
Manual 3 – Lensectomy Utilizing Vitreous Suctions Cutters
Manual 4 – Pupillary Membrane Removal

Grants Awarded:

National Institutes of Health
$224,067/year June 1987 – May 1992
Experimental Massive Periretinal Proliferation

Co-Director, Grant EY-05571
National Institutes of Health
$328,312/year September 1985 – December 1990
Multi-Center trial for the use of silicone oil for retinal detachment with proliferative vitreoretinopathy

National Institutes of Health
$130,857/year May 1983 – April 1986
Experimental Massive Periretinal Proliferation

National Institutes of Health
$240,000 April 1980 – March 1983
Experimental Massive Periretinal Proliferation (NIH)

UCSF Academic Senate
$6,500 June 1985 – May 1986
Tissue Culture of Retinal Pigment Epithelium and Implantation into the Subretinal Space

VA Research Development Program
$40,000/year February 1982 – January 1984
Merit Review – Experimental Iris Neovascularization

VA Research Development Program
$35,000/year February 1979 – January 1980
Merit Review – The Mammalian Retinal Pigment Epithelium Physiologic and Anatomic Studies

VA Research Development Program
$20,000/year July 1976 – June 1979
Merit Review – Mechanisms of Retinal Edema

VA Research Development Program
$5,000/year July 1976 – June 1979
Electrolyte & Water Transport Across the Retinal Pigment Epithelium Utilizing In Vitro Mammalian Preparation

Fight For Sight
$5,000 September 1975 – August 1976
Treatment for Experimental Retinal Edema

National Society for the Prevention of Blindness:
Immunologic Mediation of Permeability Changes in the
Choriocapillaris, Bruch’s Membrane and the Retinal Pigment Epithelium

Bibliography:

1. Molnar Z, Stern WH, Stoltzner GH: Cytoplastic tubular structures in pigmented villonodular synovitis. Arthritis Rheum 14:784, 1971.

2. Ernest JT, Stern WH: Internal limiting membrane detachment in branch retinal vein obstruction. Am J Ophthalmol 78:324, 1974.

3. Stern WH, Ernest JT: Intracranial ophthalmic artery aneurysm. Am J Ophthalmol 80:203, 1975.

4. Stern WH, Ernest JT: Microsphere occlusion of the choriocapillaris in Rhesus monkeys. Am J Ophthalmol 78:438, 1974.

5. Newell FW, Stern WH: The natural course of idiopathic serous detachment of the macula (central serous choroidopathy). An Inst Barraquer 12:578, 1975.

6. Newell, FW, Stern WH: Heteromorphic pigment dystrophy (butterfly) of the retina. Acta XXII Concilium Ophthalmologicum 2:578, 1976.

7. Ernest JT, Stern WH, Archer DB: Submacular choroidal
circulation. Am J Ophthalmol 81:574, 1976.

8. Ernest JT, Stern WH, Trimble JL: The effect of mannitol infusion on retinal function and oxygen tension. Invest Ophthalmol 16(7):670, 1977.

9. Snead JW, Stern WH, Whitcober JP, Okumoto M: Lysteria monocytogenes endophthalmitis. Am J Ophthalmol 84:337, 1977.

10. Stern WH, Modal K: Vitrectomy instrumentation in the management of total anterior chamber hyphema and control of rebleeding during hyphema extraction. Ophthalmic Surg 10(1):34, 1979.

11. Steinberg, RH, Miller SS, Stern WH: Initial observations on the isolated retinal pigment epithelium – Choroid of the cat. Invest Ophthalmol 17(7):675, 1978.

12. Collin, JRO, Beard CW, Stern WH, Schoengarth D: Blepharochalasis. Br J Ophthalmol 63(8):5442-46, 1979.

13. Scott JF, Stern WH: Radial buckling of posterior retinal tears. Am J Ophthalmol 88:41, 1979.

14. Stern WH: An integrated approach to vitrectomy instrumentation. Am J Ophthalmol 89:830, 1980.

15. Stern WH, Ernest JT, Steinberg RH, et al: Interrelationships between the retinal pigment epithelium and the neurosensory retina. Aust J Ophthalmol 8(4):281, 1980.

16. Stern WH, Archer D: Retinal venous occlusion. Annual Rev Med 32:101, 1981.

17. Stern WH: Anterior segment vitrectomy. Aust J Ophthalmol 9:3, 1981.

18. Anderson DH, Stern WH, Fisher SK, Erickson PA, Borgula GA: The onset of pigment epithelium proliferation following retinal detachment. Invest Ophthalmol 21:10, 1981.

19. Stern WH, Anderson DH, Fisher SK, et al: Anatomical recovery following retinal detachment: Clinicopathologic correlations. Aust J Ophthalmol 9:143, 1981.

20. Stern WH, Fisher SK, Anderson DH, O’Donnell JJ, Erickson PA, Lewis GP, Guerin CJ, Borgula GA, McDermott MA: Epiretinal cellular proliferation after vitrectomy. Am J Ophthalmol 93:737, 1982.

21. Newman PE, Gosheh R, Tabbara K, O’Connor GR, Stern WH: The role of hypersensitivity reactions to toxoplasma antigens in experimental toxoplasmosis in non-human primates. Am J Ophthalmol 94:159, 1982.

22. Stern WH, Lewis GP, Erickson PA, Guerin CJ, Anderson DH, Fisher SK, O’Donnell JJ: Fluorouracil therapy of proliferative vitreoretinopathy after vitrectomy. Am J Ophthalmol 96:32-42, 1983.

23. Stern WH, Guerin CJ, Erickson PA, Lewis GP, Anderson DH, Fisher SK: Ocular toxicity of fluorouracil after vitrectomy. Am J Ophthalmol 96:43-51, 1983.

24. Pruisner PE, Butler A, Yavitz EQ, Stern WH: Metastatic adenocarcinoma presenting as bilateral blindness. Ann Ophthalmol 15:653-656, 1983.

25. Anderson DH, Stern WH, Fisher SK, Erickson PA, Borgula GA: Retinal detachment in the cat: Photoreceptor interface in retinal detachment. Invest Ophthalmol Vis Sci 24(7):906-926, 1983.

26. Erickson PA, Fisher SK, Anderson DH, Stern WH, Borgula GA: Retinal detachment in the cat: The outer nuclear and outer plexiform layers. Invest Ophthalmol Vis Sci 24(7):927-942, 1983.

27. Stern WH: Argon laser photomydriasis during vitrectomy surgery. Am J Ophthalmol 99:366, 1985.

28. Heath TD, Lopez NG, Stern WH, Papahadjopoulos D: 5-Fluoroorotate: A new liposome-dependent drug. Fed Eur Biochem Soc 187:73, 1985.

29. Lambert SR, Stern WH: Methicillin and gentamicin resistant Staphylococcus epidermidis endophthalmitis following intraocular surgery. Am J Ophthalmol 99:725, 1985.

30. Stern WH, Willens R: Integration of vitrectomy instrumentation. Am J Ophthalmol 100:856, 1985.

31. Stern WH, Tamura E, Jacobs RA, Pons VG, Stone RD, O’Day DM, Irvine AR: Epidemic postsurgical Candida parapsilosis endophthalmitis: Clinical findings and management of 15 consecutive cases. Ophthalmology 92:1701, 1985.

32. Heath TD, Lopez NC, Lewis GP, Stern WH: Fluoropyrimidine therapy of ocular cicatricial disease. Invest Ophthalmol Vis Sci 27:940, 1986.

33. Anderson DH, Guerin SJ, Erickson PA, Stern WH, Fisher SK: Morphological recovery in the reattached retina. Invest Ophthalmol Vis Sci 27:168, 1986.

34. Stern WH, Johnson RN, Irvine AR, Barricks Me, Boyden BS, Hilton GF, Lonn LI, Schwartz A: Extended retinal tamponade in the treatment of retinal detachment with proliferative vitreoretinopathy. Br J Ophthalmol 70:911, 1986.

35. Heath TD, Lopez NG, Piper JR, Montgomery JA, Stern WH, Papahadjopoulos D: Liposome-medicated delivery of pteridine antifolates to cells in vitro: Efficacy of methotrexate and its alpha and gamma substituents. Biochem Y Biophys Acta 862:72, 1986.

36. Jaffe GJ, Stern WH: Pale centered retinal hemorrhage following vitrectomy. Arch Ophthalmol 105:25, 1987.

37. Goodman D, Stern WH: Oral ketoconazole therapy of fungal endophthalmitis. Arch Ophthalmol 105:172, 1987.

38. Johnson RN, Balyeat E. Stern WH: Heparin prophylaxis for intraocular fibrin. Ophthalmology 94:597, 1987.

39. Klein RF, Feingold KR, Morgan C, Stern WH, Siperstein MD: Relationship of muscle capillary basement membrane thickness and diabetic retinopathy. Diabetes Care 10:195, 1987.

40. Stern WH, Heath TD, Lewis GP, Guerin CJ, Erickson PA, Lopez NG, Hong KH: Clearance and localization of the intravitreal liposomes in the aphakic vitrectomized eye. Invest Opthalmol Vis Sci 28:907, 1987.

41. Heath TD, Lopez NG, Lewis GP, Stern WH: Antiproliferative and anticontractile effects of fluoroorotate: Potentiation by incorporation into liposomes. Invest Ophthalmol Vis Sci 28(8):1365-1371, 1987.

42. Manka R. Nozik R, Stern WH: Intraocular Staphylococcus aureus abscess masquerading as chronic uveitis. Am J Ophthalmol 105:555, 1988.

43. Good W, Stern WH: Re-operation for nonophthalmic uveal effusion following laser trabeculoplasty. Am J Ophthalmol 106:234, 1988.

44. Madiera D, Stern WH: Iris suture hook for pupillary dilation in vitreoretinal surgery. Am J Ophthalmol 106:743, 1988.

45. Roussel TJ, Stern WH, Goodman DF, Whitcher JP: Postoperative mycobacterial endophthalmitis. Am J Ophthalmol 107:403, 1989.

46. Lean JS, Stern WH, Irvine AR, Azen SP, and the Silicone Study Group: Classification of proliferative vitreoretinopathy used in the Silicone Study. Ophthalmology 96:765, 1989.

47. Hwang D. Stern WH, Swang P, MacGowan-Smith EA: Collagen shield enhancement of topical dexamethasone penetration. Arch Ophthalmol 107:1375, 1989.

48. Murray TG, Stern WH, Chin DH, MacGowan-Smith EA: Collagen shield heparin delivery for prevention postoperative fibrin. Arch Ophthalmol 108:104, 1990.

49. Heath TD, Brown CS, Stern WH: Ocular cicatricial disease: Drug effects in vitro on cell proliferation contraction and visibility (submitted for publication to IOVS).

50. McCuen BW, Azen SP, Stern WH, et al: Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy. Silicone Study Report No. 3. Retina 13:279, 1993.

51. Heath TD, Brown CS, Stern WH: Ocular cicatricial disease. Drug effects in vitro on cell proliferation, contraction and viability. Invest Ophthalmol Vis Sci 31(7):1245-51, 1990.

52. Kim RY, Stern WH: Retinoids and butyrate modulate fibroblast growth and contraction of collagen matrices. Invest Ophthalmol Vis Sci 31(6):1183-6, 1990.

53. Murray TG, Stern WH, Chin DH, et al: Collagen shield heparin delivery for prevention of postoperative fibrin. Arch Ophthalmol 108(1):104-6, 1990.

54. Freeman WR, Stern WH, Gross JG, et al: Pathologic observations made by retinal biopsy. Retina 10(3):195-204, 1990.

55. Stern WH, Francis RR, Perimutter SB: Macular degeneration; coping with age-related vision loss. Krames Communications (San Bruno, California), 1990.

56. Stern WH: Complications of vitrectomy. Int Ophthalmol Clin 32(4):205-12, 1992.

57. Stern WH, Flynn HW Jr., Fournier JH, et al: Treating diabetic retinopathy; setting your sights on saving your vision. Krames Communications (San Bruno, California), 1996.

58. Stern WH: Keeping an eye on age-related macular degeneration. Healthline 17(8):6-7, 11, 1998.

59. Pollack AL, McDonald HR, Ai E, et al: Sympathetic ophthalmia associated with pars plana vitrectomy without antecedent penetrating trauma. Retina 21(2):146-54, 2001.

Textbooks:

1. Ernest JT, Archer DB, Weiter JM, Stern WH: The Submacular Choroidal Circulation. In: Vitreous Surgery and Advances in Fundus Diagnosis and Treatment, Freeman HM, Hirose T, Scheoens CL (Eds). New York, Appleton Century-Crofts, 1977, p. 529.

2. Vitrectomy Techniques for the Anterior Segment Surgeon: A Practical Approach, Stern WH, Diddie KR, Smith RE (Eds). New York, Grune and Stratton, 1983.

3. Stern WH, Heath TD: Drug Delivery Systems for the Treatment of PVR. In: Retinal Diseases: Medical and Surgical Management, Ryan SJ, Glaser BM (Eds). St. Louis, CV Mosby, 1988.

4. Stern WH, Lean TS: Intraocular Silicone Oil vs. Gas in the Management of Proliferative Vitreoretinopathy (PVR): A Multicenter Clinical Study. In: Proliferative Vitreoretinopathy, Freeman HM (Ed). New York, Springer-Verlag, 1988, pp. 88-96.

5. Stern WH, Fungal Endophthalmitis. In: Current Ocular Therapy, Fraunfelder FT, Roy FH (Eds). Philadelphia, WB Saunders, 1989.

6. Stern WH, Tornambe WC: Automated Injection Device for Traumatic Retinopexy. In: Pneumatic Retinopathy: A Clinical Symposium. Tornambe P (Ed). Ocular Resources, Des Plaines, Illinois. (In Press).

Monographs:

1. Vitrectomy Microsurgery. Stern WH (Ed). San Mateo, Home Publishing, 1978.

2. Hilton GF, Stern WH: Vitreoretinal Surgery: An English Language Bibliography. University of California Press, 1985.

3. Stern WH, O’Donnell FE: Vitrectomy Techniques for the General Ophthalmologist. Module, Am Acad Ophthalmol, 1987.